WebbA data.frame of HyPrColoc results: each row is a cluster of colocalized traits or is coded NA (if no colocalization is identified) If snpscores=TRUE: additionally returns a list of … Webb25 juli 2024 · hyprcoloc is a function used to identify clusters of colocalized traits and candidate causal SNPs in genomic regions hyprcoloc: HyPrColoc in jrs95/hyprmtc: …
A fast and efficient colocalization algorithm for identifying shared ...
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A suggested shared aetiology of dementia - a colocalization study
HyPrColoc is an efficient deterministic Bayesian divisive clustering algorithm using GWAS summary statistics that can detect colocalization across vast numbers of traits simultaneously. Functions hyprcoloc - identifies clusters of colocalized traits and candidate causal SNPs using the HyPrColoc Bayesian divisive … Visa mer hyprcoloc - identifies clusters of colocalized traits and candidate causal SNPs using the HyPrColoc Bayesian divisive clustering algorithm. Visa mer # Regression coefficients and standard errors from ten GWAS studies (Traits 1-5, 6-8 & 9-10 colocalize) betas <- hyprcoloc::test.betas head(betas) ses <- hyprcoloc::test.ses head(ses) # Trait names and SNP IDs … Visa mer Try replacing 3 above with previous package version: 1. install_github("jrs95/hyprcoloc", build_opts = c("--no-resave-data", "--no-manual"), build_vignettes = TRUE) # Note there is no "prior.c" parameter in … Visa mer WebbHyPrColoc provides for each cluster three different types of output: (1) a PP that all phenotypes in the cluster share a common genetic signal; (2) a regional association probability that all the... WebbIt’s possible — and ZutaCore’s partnership with the world's digital infrastructure company, Equinix, is proof. By combining Equinix’s sustainable data centers and global bare metal computing platform with ZutaCore’s liquid cooling technology, we’ve created an “EZ” solution to the issue of technical-infrastructure sustainability. himalaya cucumber and coconut soap